SHELDON: Perhaps he’s at a sensitive point in his menstrual cycle.
WOLOWITZ: Are you saying he’s man-struating?
KOOTHRAPPALI: Big or small, I don’t like rabbits. They always look like they are about to say something, but they never do.
SHELDON: Rabbits do have a respiratory system that would support great size – and, on a side note, they are one of the few mammals whose scrotum is in front of the penis.
KOOTHRAPPALI: Maybe that’s what they want to talk about.
WOLOWITZ: How about this for a topic: Why is Leonard being a giant douche? Assuming giant douches are possible.
SHELDON: Of course they are. Leonard’s being one.
STUART: Are you guys still on for bowling tonight?
SHELDON: Oh, yes. In fact, I’ve prepared some trash talk for the occasion: You bowl like your mamma. Unless, of course, she bowls well, and then you bowl nothing like her.
SHELDON (to Penny): In this particular case, your lack of femininity works to our advantage.
PENNY: It’s always nice chatting with you, Sheldon.
PENNY: Thinly-veiled contempt.
SHELDON: Remember 7:00. Pacific Daylight Time.
PENNY: Bite me.
SHELDON: Please reserve that butch spirit for the lanes.
WIL WHEATON: Great, then it’s on.
SHELDON: Foolish Wil Wheaton, it was never off.
SHELDON: I so loathe you.
WIL WHEATON: That’s right, Sheldon – embrace the Dark Side.
SHELDON: That’s not even from your franchise!
(Did I miss any?)